Advertisement
Research Article|Articles in Press

Physical function, depressive symptoms, and quality of life with post-acute stroke care

  • Shu-Chin Yao
    Affiliations
    Division of Nursing, Chang Gung Memorial Hospital, Chiayi Branch, Taiwan
    Search for articles by this author
  • Suh-Ing Hsieh
    Affiliations
    Department of Nursing & Graduate Institute of Nursing, Chang Gung University of Science and Technology, Taiwan

    Division of Nursing, Chang Gung Memorial Hospital, Taoyuan Branch, Taiwan
    Search for articles by this author
  • Jiann-Der Lee
    Affiliations
    Department of Neurology, Chang Gung Memorial Hospital, Chiayi Branch, Taiwan
    Search for articles by this author
  • Tsui-Ping Chu
    Affiliations
    Division of Nursing, Chang Gung Memorial Hospital, Chiayi Branch, Taiwan
    Search for articles by this author
  • Jun-Yu Fan
    Correspondence
    Correspondence to: Department of Nursing & Graduate Institute of Nursing, Chang Gung University of Science and Technology, 261, Wen-Hua 1st Road, Kwei-Shan, Tao-Yuan 333-03, Taiwan. Tel.: +886-3-2118999; fax: +886-3-2118866.
    Affiliations
    Department of Nursing & Graduate Institute of Nursing, Chang Gung University of Science and Technology, Taiwan

    Division of Nursing, Chang Gung Memorial Hospital, Linkou Branch, Taiwan
    Search for articles by this author
Published:February 28, 2023DOI:https://doi.org/10.1016/j.colegn.2023.01.001

      ABSTRACT

      Background

      Few studies have investigated changes in physical function, psychological status, and quality of life (QOL) among stroke survivors receiving post-acute care (PAC). Nursing care has an important effect on patient outcomes, but there is very little evidence of nurses’ role in rehabilitation after stroke in Taiwan.

      Aim

      To investigate the trajectories of physical function, depressive symptoms, QOL, and factors associated with QOL in patients who received a hospital-based PAC program over 12 weeks after stroke.

      Methods

      A quasi-experimental design was employed and the study conducted in a teaching hospital in central Taiwan. Measurement tools included the Barthel Index, modified Rankin Scale, Instrumental Activities of Daily Living Scale, Geriatric Depression Scale, and Stroke Impact Scale. Data were collected at weeks one, four, eight and twelve after stroke. Descriptive, inferential, generalized estimating equations, and multiple linear regression analyses were performed.

      Findings

      Overall, 61 stroke survivors (mean age, 67.59 ± 15.64 years) were enrolled: 93.44% of strokes were ischaemic, and 59.02% of participants were male. Forty-one patients had received hospital-based PAC, while 20 had not. The PAC group exhibited significant improvements (all p < 0.05) in physical function recovery, depressive symptoms, and QOL from the 8th week post stroke compared with the regular care group. Functional recovery and depressive symptoms were significantly associated with QOL at weeks four, eight and twelve weeks after stroke.

      Discussion

      The hospital-based PAC program led to improved physical function, depressive symptoms, and QOL in patients over the 12 weeks following stroke. Physical function and depression after stroke were factors significantly associated with the patients’ QOL.

      Conclusion

      Both functional and psychological recovery impact the QOL of stroke survivors. Nurses are responsible for enhancing stroke survivors’ functional activities, recognising and supporting their psychological issues, and improving their QOL via interventions implemented during the PAC rehabilitation program.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Collegian
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

      1. American Heart Association (2022). Emotional and Behavioral Effects of Stroke. 〈https://www.stroke.org/en/about-stroke/effects-of-stroke/emotional-effects-of-stroke〉.

        • Avan A.
        • Digaleh H.
        • Di Napoli M.
        • Stranges S.
        • Behrouz R.
        • Shojaeianbabaei G.
        • et al.
        Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017.
        BMC Medicine. 2019; 17191https://doi.org/10.1186/s12916-019-1397-3
        • Baillon S.
        • Dennis M.
        • Lo N.
        • Lindesay J.
        Screening for depression in Parkinson’s disease: the performance of two screening questions.
        Age and Ageing. 2014; 43: 200-205https://doi.org/10.1093/ageing/aft152
        • Banks J.L.
        • Marotta C.A.
        Outcomes validity and reliability of the modified Rankin Scale: implications for stroke clinical trials: a literature review and synthesis.
        Stroke. 2007; 38: 1091-1096https://doi.org/10.1161/01.STR.0000258355.23810.c6
        • Blöchl M.
        • Meissner S.
        • Nestler S.
        Does depression after stroke negatively influence physical disability? A systematic review and meta-analysis of longitudinal studies.
        Journal of Affective Disorders. 2019; 247: 45-56https://doi.org/10.1016/j.jad.2018.12.082
        • Chien S.H.
        • Sung P.Y.
        • Liao W.L.
        • Tsai S.W.
        A functional recovery profile for patients with stroke following post-acute rehabilitation care in Taiwan.
        Journal of the Formosan Medical Association. 2020; 119: 254-259https://doi.org/10.1016/j.jfma.2019.05.013
        • Clarke D.J.
        Nursing practice in stroke rehabilitation: systematic review and meta-ethnography.
        Journal of Clinical Nursing. 2014; 23: 1201-1226https://doi.org/10.1111/jocn.12334
        • Donkor E.S.
        Stroke in the 21st century: a snapshot of the burden, epidemiology, and quality of life.
        Stroke Research and Treatment. 2018; 20183238165https://doi.org/10.1155/2018/3238165
        • Dong L.
        • Williams L.S.
        • Brown D.L.
        • Case E.
        • Morgenstern L.B.
        • Lisabeth L.D.
        Prevalence and course of depression during the first year after mild to moderate stroke.
        Journal of the American Heart Association. 2021; 10e020494https://doi.org/10.1161/JAHA.120.020494
        • Duncan P.W.
        • Lai S.M.
        • van Culin V.
        • Huang L.
        • Clausen D.
        • Wallace D.
        Development of a comprehensive assessment toolbox for stroke.
        Clinics in Geriatric Medicine. 1999; 15: 885-915
        • Han D.S.
        • Lin C.W.
        • Lu L.
        • Hsiao M.Y.
        • Wu C.H.
        • Liang H.W.
        • et al.
        Taiwan guidelines for stroke rehabilitation.
        Taiwan Rehabilitation Medicine Journal. 2016; 44: 1-9https://doi.org/10.6315/2016.44(1)01
        • Heikinheimo T.
        • Chimbayo D.
        Quality of life after first-ever stroke: an interview-based study from Blantyre, Malawi.
        Malawi Medical Journal. 2015; 27: 50-54https://doi.org/10.4314/mmj.v27i2.4
        • Hsien H.H.
        • Liou W.C.
        • Yang Y.H.
        Post-acute care improves daily activity functions of stroke patients: an effectiveness analysis.
        Journal of Gerontology and Gerontology of Taiwan. 2015; 10: 159-171https://doi.org/10.29461/TGG.201508_10(3).0003
        • Hsieh C.Y.
        • Tsao W.C.
        • Lin R.T.
        • Chao A.C.
        Three years of the nationwide post-acute stroke care program in Taiwan.
        Journal of the Chinese Medical Association. 2018; 81: 87-88https://doi.org/10.1016/j.jcma.2017.09.003
        • Hu J.
        • Ma L.
        • Yang Z.Y.
        Does citalopram effectively treat post-stroke depression?: a protocol for systematic review and meta analysis.
        Medicine. 2020; 99e20608https://doi.org/10.1097/MD.0000000000020608
        • Huang H.C.
        • Tsai J.Y.
        • Liu T.C.
        • Sheng W.Y.
        • Lin T.C.
        • Lin C.W.
        • et al.
        Functional recovery of stroke patients with postacute care: a retrospective study in a northern medical center.
        Journal of the Chinese Medical Association. 2019; 82: 424-427https://doi.org/10.1097/JCMA.0000000000000076
        • IBM Corp
        IBM SPSS statistics for windows, version 22.0.
        IBM Corp, Armonk, NY2013
        • Jørgensen T.S.
        • Wium-Andersen I.K.
        • Wium-Andersen M.K.
        • Jørgensen M.B.
        • Prescott E.
        • Maartensson S.
        • et al.
        Incidence of depression after stroke, and associated risk factors and mortality outcomes, in a large cohort of Danish patients.
        JAMA Psychiatry. 2016; 73: 1032-1040https://doi.org/10.1001/jamapsychiatry.2016.1932
        • Kadar M.
        • Ibrahim S.
        • Razaob N.A.
        • Chai S.C.
        • Harun D.
        Validity and reliability of a Malay version of the Lawton Instrumental Activities of Daily Living Scale among the Malay speaking elderly in Malaysia.
        Australian Occupational Therapy Journal. 2018; 65: 63-68https://doi.org/10.1111/1440-1630.12441
        • Lai C.L.
        • Tsai M.M.
        • Luo J.Y.
        • Liao W.C.
        • Hsu P.S.
        • Chen H.Y.
        Post-acute care for stroke—a retrospective cohort study in Taiwan.
        Patient Preference and Adherence. 2017; 11: 1309-1315https://doi.org/10.2147/PPA.S136041
        • Lawton M.P.
        • Brody E.M.
        Assessment of older people: self-maintaining and instrumental activities of daily living.
        The Gerontologist. 1969; 9: 179-186
        • Lee W.J.
        • Chou M.Y.
        • Peng L.N.
        • Liang C.K.
        • Liu L.K.
        • Liu C.L.
        • et al.
        Predicting clinical instability of older patients in post-acute care units: a nationwide cohort study.
        Geriatrics and Gerontology International. 2014; 14: 267-272https://doi.org/10.1111/ggi.12083
        • Liang P.J.
        • Lin P.S.
        Reliability and validity of the Stroke Impact Scale 3.0. In Taiwanese stroke patients.
        Formosan Journal of Physical Therapy. 2016; 41: 28-36https://doi.org/10.6215/FJPT.PTS1433262535
        • Mahoney F.I.
        • Barthel D.W.
        Functional evaluation: the Barthel Index.
        Maryland State Medical Journal. 1965; 14: 61-65
        • Medeiros G.C.
        • Roy D.
        • Kontos N.
        • Beach S.R.
        Post-stroke depression: a 2020 updated review.
        General Hospital Psychiatry. 2020; 66: 70-80https://doi.org/10.1016/j.genhosppsych.2020.06.011
        • Meng X.
        • Chen X.
        • Liu Z.
        • Zhou L.
        Nursing practice in stroke rehabilitation: perspectives from multi-disciplinary healthcare professionals.
        Nursing and Health Sciences. 2020; 22: 28-37https://doi.org/10.1111/nhs.12641
      2. Ministry of Health and Welfare(2021). Executive Yuan. 2020 Cause of Death Statistics. 〈https://www.mohw.gov.tw/cp-5256-63399-2.html〉.

        • Mitchell A.J.
        • Sheth B.
        • Gill J.
        • Yadegarfar M.
        • Stubbs B.
        • Yadegarfar M.
        • et al.
        Prevalence and predictors of post-stroke mood disorders: a meta-analysis and meta-regression of depression, anxiety and adjustment disorder.
        General Hospital Psychiatry. 2017; 47: 48-60https://doi.org/10.1016/j.genhosppsych.2017.04.001
      3. National Health Insurance Administration of Taiwan Ministry of Health and Welfare, Executive Yuan (2022). Post-acute Care-Cerebrovascular Diseases (2020.04.10 update). (In Chinese). 〈https://www.nhi.gov.tw/Content_List.aspx?n=5A0BB383D955741C&topn=D39E2B72B0BDFA15〉 [Accessed 5 July 2022].

        • Peng L.N.
        • Lu W.H.
        • Liang C.K.
        • Chou M.Y.
        • Chung C.P.
        • Tsai S.L.
        • et al.
        Functional outcomes, subsequent healthcare utilization, and mortality of stroke postacute care patients in Taiwan: a nationwide propensity score-matched study.
        Journal of the American Medical Directors Association. 2017; 18: 990.e7-990.e12https://doi.org/10.1016/j.jamda.2017.06.020
        • Rudberg A.S.
        • Berge E.
        • Gustavsson A.
        • Näsman P.
        • Lundström E.
        Long-term health-related quality of life, survival and costs by different levels of functional outcome six months after stroke.
        European Stroke Journal. 2018; 3: 157-164https://doi.org/10.1177/2396987317753444
        • Schindel D.
        • Schneider A.
        • Grittner U.
        • Jöbges M.
        • Schenk L.
        Quality of life after stroke rehabilitation discharge: a 12-month longitudinal study.
        Disability and Rehabilitation. 2021; 43: 2332-2341https://doi.org/10.1080/09638288.2019.1699173
        • Sheikh J.I.
        • Yesavage J.A.
        Geriatric Depression Scale (GDS): recent evidence and development of a shorter version.
        Clinical Gerontologist: The Journal of Aging and Mental Health. 1986; 5: 165-173https://doi.org/10.1300/J018v05n01_09
        • Towfighi A.
        • Ovbiagele B.
        • El Husseini N.
        • Hackett M.L.
        • Jorge R.E.
        • Kissela B.M.
        • et al.
        Poststroke depression: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association.
        Stroke. 2017; 48: e30-e43https://doi.org/10.1161/STR.0000000000000113
        • Uyttenboogaart M.
        • Stewart R.E.
        • Vroomen P.C.
        • De Keyser J.
        • Luijckx G.J.
        Optimizing cutoff scores for the Barthel Index and the modified Rankin Scale for defining outcome in acute stroke trials.
        Stroke. 2005; 36: 1984-1987
        • Wafa H.A.
        • Wolfe C.D.A.
        • Emmett E.
        • Roth G.A.
        • Johnson C.O.
        • Wang Y.
        Burden of stroke in Europe: thirty-year projections of incidence, prevalence, deaths, and disability-adjusted life years.
        Stroke. 2020; 51: 2418-2427https://doi.org/10.1161/STROKEAHA.120.029606
        • Wang S.
        • Wang C.X.
        • Zhang N.
        • Xiang Y.T.
        • Yang Y.
        • Shi Y.Z.
        • et al.
        The association between post-stroke depression, aphasia, and physical independence in stroke patients at 3-month follow-up.
        Frontiers in Psychiatry. 2018; 9374https://doi.org/10.3389/fpsyt.2018.00374
        • Weng S.-C.
        • Hsu C.-Y.
        • Shen C.-C.
        • Huang J.-A.
        • Chen P.-L.
        • Lin S.-Y.
        Combined functional assessment for predicting clinical outcomes in stroke patients after post-acute care: a retrospective multi-center cohort in central Taiwan.
        Frontiers in Aging Neuroscience. 2022; 14834273https://doi.org/10.3389/fnagi.2022.834273
        • Wilson J.T.
        • Hareendran A.
        • Hendry A.
        • Potter J.
        • Bone I.
        • Muir K.W.
        Reliability of the modified Rankin Scale across multiple raters: benefits of a structured interview.
        Stroke. 2005; 36: 777-781https://doi.org/10.1161/01.STR.0000157596.13234.95
        • Winstein C.J.
        • Stein J.
        • Arena R.
        • Bates B.
        • Cherney L.R.
        • Cramer S.C.
        • et al.
        Guidelines for adult stroke rehabilitation and recovery: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.
        Stroke. 2016; 47: e98-e169https://doi.org/10.1161/STR.0000000000000098
        • Wong H.J.
        • Lua P.L.
        • Harith S.
        • Ibrahim K.A.
        Health-related quality of life profiles and their dimension-specific associated factors among Malaysian stroke survivors: a cross sectional study.
        Health and Quality of Life Outcomes. 2021; 19210https://doi.org/10.1186/s12955-021-01847-0
        • Wu K.Y.
        • Wu S.C.
        • Hung Y.N.
        • Wu C.C.
        • Lin L.C.
        • Hu H.H.
        The need for post-acute care for stroke patients in Taiwan.
        Taiwan Gong Gong Wei Sheng Za Zhi. 2012; 31 (in Chinese)251
        • Wu W.J.
        • Chang I.C.
        • Lin C.T.
        • Wang S.C.
        • Ku Y.R.
        The effects of enhanced physical therapy on post-acute stroke patients.
        Formosan Journal of Physical Therapy. 2016; 41: 165-166
        • Yesavage J.A.
        • Brink T.L.
        • Rose T.L.
        • Lum O.
        • Huang V.
        • Adey M.
        • et al.
        Development and validation of a geriatric depression screening scale: a preliminary report.
        Journal of Psychiatric Research. 1982; 17: 37-49https://doi.org/10.1016/0022-3956(82)90033-4
        • Ytterberg C.
        • Cegrell L.
        • von Koch L.
        • Wiklander M.
        Depression symptoms 6 years after stroke are associated with higher perceived impact of stroke, limitations in ADL and restricted participation.
        Scientific Reports. 2022; 127816https://doi.org/10.1038/s41598-022-11097-9